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An overview of mycobacterium tuberculosis, the microorganism that causes tuberculosis including method pathogenicity, treatment programmes and the world wide implications of tuberculosis. -- 1,560 words; MLA

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TUBERCULOSIS

Among us today there are thousands of diseases out in the world, most are curable, some
don't even have names. Well by the end of this paper you should learn about one more
disease called Tuberculosis that will help you understand more about the infectious
agents that threaten our lives today and how to control them, especially Tuberculosis.
Tuberculosis is the increasingly spreading disease in the world and causes more deaths
today then ever before. ( www. homepage.holowww.com) TB Global Emergency)) It kills 8,000
people a day that is 2-3 million people a year. It has surpassed the Aids community
overall and is responsible for more deaths among the young and adults in the world today.
( www. homepage.holowww.com) TB Global Emergency)) 
To find out why Tuberculosis is causing all these problems you have to go to the source
and find out what it is. Tuberculosis (TB), chronic or acute bacterial infection that
primarily attacks the lungs. Tuberculosis is caused by the bacterium Mycobacterium
tuberculosis. (AMA) Mycobacterium tuberculosis is a bacteria that is an obligate aerobe,
rod shaped, acid fast, that has a characteristic mycolic acid cell wall. Generation time
(time to create two bacteria from one) 18-24 hours Diagnostic test - PPD skin test, and
x-rays. (Merck's Manual) Tuberculosis is a disease that can damage a person's lungs and
causes serious illness. 
TB is usually transmitted by bacteria-carrying air droplets that are released when a
person sick with TB coughs, sneezes, or speaks. Inhaled bacteria lodge in the lungs and
multiply. Only 5 to 10 percent of those infected actually become sick. Once it is
contracted, the disease can occur in a primary and a secondary stage. (AMA) When this
occurs is causes the two stages of TB. The Primary TB produces no noticeable symptoms.
Immune system cells ingest the TB bacteria and transport them to the lymph nodes where
they may be destroyed or inhibited. TB is not contagious in the early stage. If the
bacteria multiply, then active primary tuberculosis develops. Symptoms include coughing,
night sweats, weight loss, and fever. If the bacteria are inhibited, the immune cells
form a wall around inactive bacteria, producing a tubercle. As long as the immune system
remains strong, the TB bacteria are inactive, and they may remain dormant for many years.
If the immune system becomes weakened, the tubercle opens, and the infection may develop
into secondary TB. (AMA)
In secondary TB, bacteria destroy tissue in the lungs and may spread to the rest of the
body. Fluid or air may collect between the lungs and the lining of the lungs, while
tubercles continue to develop, destroying lung tissue. Coughing of blood or phlegm may
occur. At this secondary stage, carriers of TB can infect others. (AMA)
So how big of a problem is Tuberculosis? In 1993, the World health Organization (WHO)
took an unprecedented step and declared tuberculosis a global emergency, so great was the
concern about the modern TB epidemic. It is estimated that between now and 2020, nearly
one billion more people will be newly infected, 200 million people will get sick, and 70
million will die from TB - if control is not strengthened. People with the active disease
left untreated, will infect on average between 10 and 15 people in each year. Someone in
the world is newly infected with TB every second. Nearly one percent of the world's
population is infected with TB each year. (trc-chennai.org/dots.htm)
Why isn't it such a big deal? Why, don't we hear about it in the United States everyday?
The problem is that most of the world's population that is infected with the TB disease
are stationed in the poor societies of the world. For instance the worlds biggest
Tuberculosis outbreak is in poor countries like India, and small African countries. These
are the countries that hold the most population and a disease outbreak in one of them
will spread with no control cause they have no technology to help cure them or knowledge
to stop the spreading of the deadly disease. TB kills 2 to 3 million people each year. TB
accounts for more than one-quarter of all preventable adult deaths in developing
countries. 7 to 8 million people around the world become sick with TB each year. Between
1993 and 1996 there was a 13 percent increase in TB cases worldwide. Nearly 2 million TB
cases per year occur in sub-Saharan Africa. Nearly 3 million TB cases per year occur in
Southeast Asia. Over a quarter of a million TB cases per year occur in Eastern Europe.
(www.tuberculosis.net)
When a country of large magnitude gets infected how do they stop the cure? The answer is
through industrialized countries like us. TB treatment costs around US $2,000 per
patient, but rises more than 100-fold to up to US $250,000 per patient with MDR-TB.
(MDR-TB is the multidrug-resistant (MDR) strains, defined as resistant to the two most
important drugs, isoniazid and rifampicin) This goes through us the taxpayers or smaller
organizations like the D.O.T.S. (Directly Observed Treatment, Short-course). D.O.T.S
produces cure rates of up to 95 percent even in the poorest countries. D.O.T.S prevents
new infections and the development of MDR-TB. There effective procedure is to health and
community workers and trained volunteers observe and record patients swallowing the
correct dosage of anti-TB medicines for six to eight months. The most common anti-TB
drugs are isoniazid, rifampicin, pyrazinamide, streptomycin and ethambutol.
(trc-chennai.org/dots.htm) The problem is funding and without it D.O.T.S can't stop the
disease from spreading. Other techniques in curing the disease are in the Alternative
Medicine. Countries back east are curing TB by herbalism, using antipyretics or
febrifuges, herbs use to fight pathogens. Other treatments used are Naturopathy, which is
the orthodox treatment of dieting on fresh fruits, limiting diary products. (Alternative
Healthcare) These orthodox treatments can cause a cure but if not taken correctly with a
doctor's permission can cause severe illness.
In conclusion we all know how serious Tuberculosis is and at the same time we are
neglectful in our awareness of other potentially lethal pathogens that are out there. We
are smart enough to recognize what is out there, how Tuberculosis is transmitted and how
it is possible to prevent this measure of Tuberculosis disease from spreading and keeping
us healthy and free from the TB disease.
Bibliography
science books any

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